From Proteopedia
proteopedia link proteopedia link Crystal structure of amprenavir (APV) in complex with a drug resistant HIV-1 protease variant (I50L/A71V).
Structural highlights
3em3 is a 2 chain structure with sequence from Hiv-1 m:b_arv2/sf2 . Full crystallographic information is available from OCA . For a guided tour on the structure components use FirstGlance .
Ligands: ,
Related: 3ekp , 3ekq , 3ekt , 3ekv , 3ekw , 3ekx , 3eky , 3el0 , 3el1 , 3el4 , 3el5 , 3em4 , 3em6
Gene: gag-pol, HIV-1 subtype B (HIV-1 M:B_ARV2/SF2 )
Activity: HIV-1 retropepsin , with EC number 3.4.23.16
Resources: FirstGlance , OCA , RCSB , PDBsum
Evolutionary Conservation
Check, as determined by ConSurfDB . You may read the explanation of the method and the full data available from ConSurf .
See Also