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1sfo
From Proteopedia
Revision as of 15:49, 29 September 2014 by OCA (Talk | contribs)
1sfo is a 12 chain structure with sequence from Saccharomyces cerevisiae. This structure supersedes the now removed PDB entry 1r9r. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The structure of an RNA polymerase II-transcribing complex has been determined in the posttranslocation state, with a vacancy at the growing end of the RNA-DNA hybrid helix. At the opposite end of the hybrid helix, the RNA separates from the template DNA. This separation of nucleic acid strands is brought about by interaction with a set of proteins loops in a strand/loop network. Formation of the network must occur in the transition from abortive initiation to promoter escape.
Structural basis of transcription: separation of RNA from DNA by RNA polymerase II.,Westover KD, Bushnell DA, Kornberg RD Science. 2004 Feb 13;303(5660):1014-6. PMID:14963331[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Westover KD, Bushnell DA, Kornberg RD. Structural basis of transcription: separation of RNA from DNA by RNA polymerase II. Science. 2004 Feb 13;303(5660):1014-6. PMID:14963331 doi:http://dx.doi.org/10.1126/science.1090839
