1v1f is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The Arabidopsis thaliana SOS3 gene encodes a calcium sensor that is required for plant salt tolerance. The SOS3 protein binds to and activates the self-inhibited SOS2 protein kinase, which mediates the expression and activities of various transporters important for ion homeostasis under salt stress. SOS3 belongs to a unique family of calcium-binding proteins that contain two pairs of EF hand motifs with four putative metal-binding sites. We report the crystal structure of a dimeric SOS3 protein in complex with calcium, and with calcium and manganese. Analytical ultracentrifugation experiments and circular dichroism measurements show that calcium binding is responsible for the dimerization of SOS3. This leads to a change in the global shape and surface properties of the protein that may be sufficient to transmit the Ca(2+) signal elicited during salt stress.
The structure of the Arabidopsis thaliana SOS3: molecular mechanism of sensing calcium for salt stress response.,Sanchez-Barrena MJ, Martinez-Ripoll M, Zhu JK, Albert A J Mol Biol. 2005 Feb 4;345(5):1253-64. Epub 2004 Dec 8. PMID:15644219[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Sanchez-Barrena MJ, Martinez-Ripoll M, Zhu JK, Albert A. The structure of the Arabidopsis thaliana SOS3: molecular mechanism of sensing calcium for salt stress response. J Mol Biol. 2005 Feb 4;345(5):1253-64. Epub 2004 Dec 8. PMID:15644219 doi:10.1016/j.jmb.2004.11.025
