This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1kqg

From Proteopedia

Revision as of 10:20, 20 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:1kqg.jpg


PDB ID 1kqg

Drag the structure with the mouse to rotate
, resolution 2.80Å
Ligands: , , , , and
Activity: Formate dehydrogenase, with EC number 1.2.1.2
Coordinates: save as pdb, mmCIF, xml



FORMATE DEHYDROGENASE N FROM E. COLI


Overview

The structure of the membrane protein formate dehydrogenase-N (Fdn-N), a major component of Escherichia coli nitrate respiration, has been determined at 1.6 angstroms. The structure demonstrates 11 redox centers, including molybdopterin-guanine dinucleotides, five [4Fe-4S] clusters, two heme b groups, and a menaquinone analog. These redox centers are aligned in a single chain, which extends almost 90 angstroms through the enzyme. The menaquinone reduction site associated with a possible proton pathway was also characterized. This structure provides critical insights into the proton motive force generation by redox loop, a common mechanism among a wide range of respiratory enzymes.

About this Structure

1KQG is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Molecular basis of proton motive force generation: structure of formate dehydrogenase-N., Jormakka M, Tornroth S, Byrne B, Iwata S, Science. 2002 Mar 8;295(5561):1863-8. PMID:11884747

Page seeded by OCA on Thu Mar 20 12:20:53 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1kqg"
Personal tools