Alanine racemase (AR) catalyzes the racemization of L-alanine to D-alanine. AR uses pyridoxal-5’-phosphate (PLP) as a cofactor. PLP binds to a lysine residue of AR. AR participates in alanine and aspartate metabolism. The antibiotic D-cycloserine is an effective inhibitor of AR.
3D Structures of alanine racemase
Updated on 16-November-2014