Catenin

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Revision as of 13:40, 19 November 2014 by Michal Harel (Talk | contribs)
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Catenins (CTN) are proteins which make complexes with cadherin.

  • α-CTN links cadherin (CDH) and α-actinin, it is encoded by 3 genes: α-E-CTN (epithelial), α-T-CTN (membrane bound), and α-N-CTN (neuronal).
  • β-CTN is a subunit of the cadherin complex. It contains Armadillo repeats which are a pair of helices forming hairpin structure.
  • γ-CTN (or plakoglobin) is a component of desmosomes and contains armadillo repeats.
  • δ-CTN is expressed in the brain and contains 10 armadillo repeats.
  • p120 CTN is another member of the CTN family.

3D Structures of Catenin

Updated on 19-November-2014

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Michal Harel, Alexander Berchansky

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