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MECDP synthase

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Revision as of 08:22, 1 December 2014 by Michal Harel (Talk | contribs)
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MECDP synthase (MECPS) participates in mevalonate-independent steroid biosynthesis. It converts 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol (2P-CDME) to 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate (MECP) and CMP. MECPS contains metal binding sites which are required for catalysis. MECPS is a potential antimalarial drug target.

3D structures of MECDP synthase

Updated on 01-December-2014

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Michal Harel, Alexander Berchansky

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