Pantothenate synthetase

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Pantothenate synthetase (PS) catalyzes the ATP-dependent condensation of pantoate and β-alanine to form pantothenate. Pantothenate (vitamin B5) biosynthesis is essential for the virulence of Mycobacterium tuberculosis thus its blockage can be used as a potential drug target.

3D structures of pantothenate synthetase

Updated on 02-December-2014

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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