1nq3
From Proteopedia
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Crystal structure of the mammalian tumor associated antigen UK114
Overview
The tumour-associated antigen UK114, isolated from goat liver, belongs to the YER057c/YIL051c/YjgF protein family, which has members in both the prokaryotes and eukaryotes. The crystal structure of a mammalian representative, goat UK114, was determined, revealing a trimeric arrangement in the crystal. It was confirmed by ultracentrifugation that UK114 is a trimer in solution. These results are in agreement with the published structures of homologues from unicellular organisms, but contrast with those reported for the rat homologue of UK114, for which a dimeric quaternary structure was proposed.
About this Structure
1NQ3 is a Single protein structure of sequence from Capra hircus. Full crystallographic information is available from OCA.
Reference
Structure and oligomeric state of the mammalian tumour-associated antigen UK114., Deriu D, Briand C, Mistiniene E, Naktinis V, Grutter MG, Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1676-8. Epub 2003, Aug 19. PMID:12925811
Page seeded by OCA on Thu Mar 20 13:00:13 2008
