Structural highlights
3ui2 is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Related: | 3deo, 3dep |
| Gene: | At2g47450, CAO, CPSRP43, T30B22.25 (Arabidopsis thaliana), At5g03940, CPSRP54, F8F6_150, FFC (Arabidopsis thaliana) |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Publication Abstract from PubMed
Chromodomains typically recruit protein complexes to chromatin and read the epigenetic histone code by recognizing lysine methylation in histone tails. We report the crystal structure of the chloroplast signal recognition particle (cpSRP) core from Arabidopsis thaliana, with the cpSRP54 tail comprising an arginine-rich motif bound to the second chromodomain of cpSRP43. A twinned aromatic cage reads out two neighboring nonmethylated arginines and adapts chromodomains to a non-nuclear function in post-translational targeting.
Chromodomains read the arginine code of post-translational targeting.,Holdermann I, Meyer NH, Round A, Wild K, Sattler M, Sinning I Nat Struct Mol Biol. 2012 Jan 8;19(2):260-3. doi: 10.1038/nsmb.2196. PMID:22231402[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Holdermann I, Meyer NH, Round A, Wild K, Sattler M, Sinning I. Chromodomains read the arginine code of post-translational targeting. Nat Struct Mol Biol. 2012 Jan 8;19(2):260-3. doi: 10.1038/nsmb.2196. PMID:22231402 doi:10.1038/nsmb.2196
