Saposin

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Saposin (Sap) is a small protein which functions as activator of lipid-degrading enzymes. They act by isolating the lipid substrate from the membrane. Sap is synthesized as a precursor – prosaposin – which contain 4 SapB active domains and 2 SapA domains which are cleaved off. For more details see Molecular Playground/Saposin C.

3D Structures of Saposin

Updated on 10-December-2014

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Michal Harel, Alexander Berchansky

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