Structural highlights
Publication Abstract from PubMed
Plasma membranes are organized into domains of different protein and lipid composition. Eisosomes are key complexes for yeast plasma membrane organization, containing primarily Pil1 and Lsp1. Here we show that both proteins consist mostly of a banana-shaped BAR domain common to membrane sculpting proteins, most similar to the ones of amphiphysin, arfaptin 2 and endophilin 2. Our data reveal a previously unrecognized family of BAR-domain proteins involved in plasma membrane organization.
Eisosome-driven plasma membrane organization is mediated by BAR domains.,Ziolkowska NE, Karotki L, Rehman M, Huiskonen JT, Walther TC Nat Struct Mol Biol. 2011 Jun 19. doi: 10.1038/nsmb.2080. PMID:21685922[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Ziolkowska NE, Karotki L, Rehman M, Huiskonen JT, Walther TC. Eisosome-driven plasma membrane organization is mediated by BAR domains. Nat Struct Mol Biol. 2011 Jun 19. doi: 10.1038/nsmb.2080. PMID:21685922 doi:10.1038/nsmb.2080
