1u9s

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spinqualitylabelsall models PDB ID 1u9s Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
, resolution 2.90Å
Ligands:
Coordinates:	save as pdb, mmCIF, xml

Crystal structure of the specificity domain of Ribonuclease P of the A-type

Overview

Large RNA molecules, such as ribozymes, fold with well-defined tertiary structures that are important for their activity. There are many instances of ribozymes with identical function but differences in their secondary structures, suggesting alternative tertiary folds. Here, we report a crystal structure of the 161-nucleotide specificity domain of an A-type ribonuclease P that differs in secondary and tertiary structure from the specificity domain of a B-type molecule. Despite the differences, the cores of the domains have similar three-dimensional structure. Remarkably, the similar geometry of the cores is stabilized by a different set of interactions involving distinct auxiliary elements.

About this Structure

1U9S is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.

Reference

Basis for structural diversity in homologous RNAs., Krasilnikov AS, Xiao Y, Pan T, Mondragon A, Science. 2004 Oct 1;306(5693):104-7. PMID:15459389

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