1y8j

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PDB ID 1y8j

Drag the structure with the mouse to rotate
, resolution 2.25Å
Ligands: , , and
Gene: MME, EPN (Homo sapiens)
Activity: Neprilysin, with EC number 3.4.24.11
Coordinates: save as pdb, mmCIF, xml



Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor


Disease

Known diseases associated with this structure: Membranous glomerulonephritis, antenatal OMIM:[120520], Neutral endopeptidase deficiency OMIM:[120520], Schizophrenia, susceptibility to OMIM:[607265]

About this Structure

1Y8J is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 15:19:42 2008

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