| Structural highlights
2xrl is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
| | Ligands: | , , |
| Related: | 2xgc, 2xpw, 1bjz, 3zqg, 2x9d, 3zqh, 2trt, 2xpv, 2vkv, 1ork, 2xge, 2x6o, 1a6i, 1qpi, 2vke, 2xgd, 1du7, 2xpt, 2xpu, 2xb5, 3zqi, 3zqf, 1bj0, 2xps, 2tct, 1bjy |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[TETR4_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
See Also
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