4lir

Structural highlights

Function

[NUP53_HUMAN] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC.^[1]

See Also

• Nucleoporin

References

1. ↑ Hawryluk-Gara LA, Shibuya EK, Wozniak RW. Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. Mol Biol Cell. 2005 May;16(5):2382-94. Epub 2005 Feb 9. PMID:15703211 doi:10.1091/mbc.E04-10-0857