Structural highlights
3kyb is a 2 chain structure with sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Ligands: | , |
| Related: | 3int, 3inr, 3gf4, 2bi7, 2bi8, 1wam |
| Gene: | glf, rfbD (Klebsiella pneumoniae) |
| Activity: | UDP-galactopyranose mutase, with EC number 5.4.99.9 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[GLF1_KLEPN] Involved in the biosynthesis of the galactose-containing O-side-chain polysaccharide backbone structure of D-galactan I which is a key component of lipopolysaccharide (LPS). Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is the biosynthetic precursor of galactofuranosyl residues.[1]
See Also
References
- ↑ Koplin R, Brisson JR, Whitfield C. UDP-galactofuranose precursor required for formation of the lipopolysaccharide O antigen of Klebsiella pneumoniae serotype O1 is synthesized by the product of the rfbDKPO1 gene. J Biol Chem. 1997 Feb 14;272(7):4121-8. PMID:9020123
