2ao7

From Proteopedia

Revision as of 13:51, 20 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:2ao7.gif


PDB ID 2ao7

Drag the structure with the mouse to rotate
, resolution 2.9Å
Ligands:
Gene: ADAM10, MADM (Bos taurus)
Activity: ADAM10 endopeptidase, with EC number 3.4.24.81
Coordinates: save as pdb, mmCIF, xml



Adam10 Disintegrin and cysteine- rich domain


Overview

Ephrin ligands presented on one cell surface associate with their receptors on the surface of a juxtaposed cell, often resulting in cell-cell repulsion. In this issue of Cell, Janes et al. (2005) show that the ephrin ligand can be proteolytically released from its membrane tether by a complex on the opposing cell composed of the ephrin receptor and an ADAM metalloprotease.

About this Structure

2AO7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

ADAM and Eph: how Ephrin-signaling cells become detached., Mancia F, Shapiro L, Cell. 2005 Oct 21;123(2):185-7. PMID:16239135

Page seeded by OCA on Thu Mar 20 15:51:58 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ao7"
Personal tools