This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.




2b3e

From Proteopedia

Revision as of 13:57, 20 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:2b3e.gif


PDB ID 2b3e

Drag the structure with the mouse to rotate
, resolution 1.36Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



Crystal structure of DB819-D(CGCGAATTCGCG)2 complex.


Overview

The crystal structure of the DNA minor groove biphenyl benzimidazole diamidine ligand DB819 has been determined, bound to the DNA sequence d(CGCGAATTCGCG)(2), at a resolution of 1.36 Angstrom. Conditions for reliable in silico docking that reproduce the observed position of the ligand in the minor groove have been determined.

About this Structure

2B3E is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Targeting the DNA minor groove with fused ring dicationic compounds: comparison of in silico screening and a high-resolution crystal structure., Campbell NH, Evans DA, Lee MP, Parkinson GN, Neidle S, Bioorg Med Chem Lett. 2006 Jan 1;16(1):15-9. Epub 2005 Nov 2. PMID:16263285

Page seeded by OCA on Thu Mar 20 15:57:03 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2b3e"
Personal tools