Structural highlights
4wuo is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , , |
| Related: | 4f7i, 2y3z, 2y40, 2y41, 2y42, 1hex |
| Activity: | 3-isopropylmalate dehydrogenase, with EC number 1.1.1.85 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[LEU3_THET8] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]
