2yqm

Structural highlights

Function

[RUFY1_HUMAN] Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Fouraux MA, Deneka M, Ivan V, van der Heijden A, Raymackers J, van Suylekom D, van Venrooij WJ, van der Sluijs P, Pruijn GJ. Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes. Mol Biol Cell. 2004 Feb;15(2):611-24. Epub 2003 Nov 14. PMID:14617813 doi:http://dx.doi.org/10.1091/mbc.E03-05-0343