Structural highlights
Function
[SFI1_SEGFL] Insecticidal toxin. Causes flaccid paralysis followed by death when injected into Heliothis virescens larvae. Does not induce any toxic effects when injected intravenously into adult mice at a dose of 1.5 mg/kg body weight. Orally active against larvae of the tomato moth (Laconobia oleracea), the rice brown planthopper (Nilaparvata lugens), and the peach-potato aphid (Myzus persicae) when fused to snowdrop lectin.[1]
References
- ↑ Fitches E, Edwards MG, Mee C, Grishin E, Gatehouse AM, Edwards JP, Gatehouse JA. Fusion proteins containing insect-specific toxins as pest control agents: snowdrop lectin delivers fused insecticidal spider venom toxin to insect haemolymph following oral ingestion. J Insect Physiol. 2004 Jan;50(1):61-71. PMID:15037094 doi:http://dx.doi.org/10.1016/j.jinsphys.2003.09.010
