Structural highlights
3r8x is a 1 chain structure with sequence from Yersinia pestis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| Gene: | fmt, y4022, YPO0241, YP_0239 (Yersinia pestis) |
| Activity: | Methionyl-tRNA formyltransferase, with EC number 2.1.2.9 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[FMT_YERPE] Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity).
