Structural highlights
4ix2 is a 4 chain structure with sequence from Vibrio cholerae o1 biovar el tor str. n16961. This structure supersedes the now removed PDB entry 4ff0. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
Ligands: | , |
Related: | 4fxs, 4fez, 4fo4, 4hlv |
Gene: | guaB, VC0767, VC_0767 (Vibrio cholerae O1 biovar El Tor str. N16961) |
Activity: | IMP dehydrogenase, with EC number 1.1.1.205 |
Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[Q9KTW3_VIBCH] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
See Also