Structural highlights
2uyh is a 3 chain structure with sequence from Haemophilus haemolyticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , |
| NonStd Res: | |
| Related: | 10mh, 1fjx, 1hmy, 1m0e, 1mht, 1skm, 1svu, 2c7o, 2c7p, 2c7q, 2c7r, 2hmy, 2uyc, 3mht, 4mht, 5mht, 6mht, 7mht, 8mht, 9mht |
| Activity: | DNA (cytosine-5-)-methyltransferase, with EC number 2.1.1.37 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[MTH1_HAEPH] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
See Also
