Structural highlights
3l21 is a 6 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , , |
| NonStd Res: | , |
| Related: | 1xxx, 2ojp |
| Gene: | dapA, MT2823, MTV002.18c, Rv2753c (Mycobacterium tuberculosis) |
| Activity: | Dihydrodipicolinate synthase, with EC number 4.2.1.52 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[DAPA_MYCTU] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA) (Probable).[1]
See Also
References
- ↑ Kefala G, Evans GL, Griffin MD, Devenish SR, Pearce FG, Perugini MA, Gerrard JA, Weiss MS, Dobson RC. Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J. 2008 Apr 15;411(2):351-60. PMID:18062777 doi:10.1042/BJ20071360
