Practical Guide to Homology Modeling

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Terminology

  • Query sequence: The amino acid sequence for which a 3D model is wanted. More commonly called the target sequence, but talking about target vs. template gets confusing.
  • Template: An empirically determined 3D protein structure with significant sequence similarity to the query.
  • Structure will be used in this article to mean three-dimensional structure.

What Is A Homology Model?

References

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Eric Martz, Juergen Haas, Jaime Prilusky

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