2g1w

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Image:2g1w.gif


PDB ID 2g1w

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NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1


Overview

The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.

About this Structure

2G1W is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:16595798

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