Structural highlights
Publication Abstract from PubMed
Pyridoxal 4-dehydrogenase catalyzes the irreversible oxidation of pyridoxal to 4-pyridoxolactone and is involved in degradation pathway I of pyridoxine, a vitamin B(6) compound. Its crystal structure was elucidated for the first time. Molecular replacement with (S)-1-phenylthanol dehydrogenase (PDB code 2EW8) was adopted to determine the tertiary structure of the NAD(+)-bound enzyme.
The crystal structure of SDR-type pyridoxal 4-dehydrogenase of Mesorhizobium loti.,Chu HN, Kobayashi J, Mikami B, Yagi T Biosci Biotechnol Biochem. 2011;75(2):388-90. Epub 2011 Feb 7. PMID:21307574[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Chu HN, Kobayashi J, Mikami B, Yagi T. The crystal structure of SDR-type pyridoxal 4-dehydrogenase of Mesorhizobium loti. Biosci Biotechnol Biochem. 2011;75(2):388-90. Epub 2011 Feb 7. PMID:21307574
