2gys

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PDB ID 2gys

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, resolution 2.70Å
Gene: CSF2RB, IL3RB, IL5RB (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



2.7 A structure of the extracellular domains of the human beta common receptor involved in IL-3, IL-5, and GM-CSF signalling


Overview

X-ray diffraction has been used to produce and refine a model of the extracellular domains of the beta common cytokine receptor. A minor improvement in resolution has resulted in improved electron-density maps, which have given a clearer indication of the position and stabilization of the key residues Tyr15, Phe79, Tyr347, His349, Ile350 and Tyr403 in the elbow region between domain 1 and domain 4 of the dimer-related molecule.

About this Structure

2GYS is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope., Carr PD, Conlan F, Ford S, Ollis DL, Young IG, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt, 6):509-13. Epub 2006 May 31. PMID:16754968

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