Structural highlights
Publication Abstract from PubMed
Group II introns are self-splicing catalytic RNAs that are thought to be ancestral to the spliceosome. Here we report the 3.65-A crystal structure of the group II intron from Oceanobacillus iheyensis in the pre-catalytic state. The structure reveals the conformation of the 5' splice site in the catalytic core and represents the first structure of an intron prior to the first step of splicing.
Crystal structure of a group II intron in the pre-catalytic state.,Chan RT, Robart AR, Rajashankar KR, Pyle AM, Toor N Nat Struct Mol Biol. 2012 Apr 8. doi: 10.1038/nsmb.2270. PMID:22484319[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Chan RT, Robart AR, Rajashankar KR, Pyle AM, Toor N. Crystal structure of a group II intron in the pre-catalytic state. Nat Struct Mol Biol. 2012 Apr 8. doi: 10.1038/nsmb.2270. PMID:22484319 doi:10.1038/nsmb.2270
