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2huw

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Revision as of 15:21, 20 March 2008 by OCA (Talk | contribs)
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Image:2huw.gif


PDB ID 2huw

Drag the structure with the mouse to rotate
, resolution 1.900Å
Ligands: and
Gene: GRB2, ASH (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand


Disease

Known diseases associated with this structure: Central hypoventilation syndrome, congenital OMIM:[100790], Haddad syndrome OMIM:[100790]

About this Structure

2HUW is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions., Benfield AP, Teresk MG, Plake HR, DeLorbe JE, Millspaugh LE, Martin SF, Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6830-5. PMID:17001728

Page seeded by OCA on Thu Mar 20 17:21:52 2008

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