Structural highlights
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
Gene PA1377 from Pseudomonas aeruginosa encodes a 177-amino-acid conserved hypothetical protein of unknown function. The structure of this protein (termed pitax) has been solved in space group I222 to 2.25 A resolution. Pitax belongs to the GCN5-related N-acetyltransferase family and contains all four sequence motifs conserved among family members. The beta-strand structure in one of these motifs (motif A) is disrupted, which is believed to affect binding of the substrate that accepts the acetyl group from acetyl-CoA.
Structure of a putative acetyltransferase (PA1377) from Pseudomonas aeruginosa.,Davies AM, Tata R, Chauviac FX, Sutton BJ, Brown PR Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 May 1;64(Pt 5):338-42., Epub 2008 Apr 24. PMID:18453699[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Davies AM, Tata R, Chauviac FX, Sutton BJ, Brown PR. Structure of a putative acetyltransferase (PA1377) from Pseudomonas aeruginosa. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 May 1;64(Pt 5):338-42., Epub 2008 Apr 24. PMID:18453699 doi:10.1107/S1744309108007665
