Structural highlights
Publication Abstract from PubMed
A designer monomeric protein with a beta alpha beta fold--two parallel beta strands connected by an alpha helix (see structure)--was constructed solely from coded amino acids. The high thermal stability of the structure is due to a large extent to tryptophan-tryptophan interactions between the two beta strands.
De novo design of a beta alpha beta motif.,Liang H, Chen H, Fan K, Wei P, Guo X, Jin C, Zeng C, Tang C, Lai L Angew Chem Int Ed Engl. 2009;48(18):3301-3. PMID:19347908[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Liang H, Chen H, Fan K, Wei P, Guo X, Jin C, Zeng C, Tang C, Lai L. De novo design of a beta alpha beta motif. Angew Chem Int Ed Engl. 2009;48(18):3301-3. PMID:19347908 doi:10.1002/anie.200805476
