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Asparaginase
From Proteopedia
Asparaginase (ASP) catalyzes the conversion of asparagine to aspartic acid (AA). ASP I is used in the food processing industry to reduce the formation of the carcinogen acrylamide in the production of starchy food products. A different kind of ASP – ASP II – is used as drug (Elspar) in the treatment of cancer such as acute lymphoblastic leukemia (ALL). The ALL cells require high concentrations of asparagine which becomes scarce when high doses of ASP are present.
3D structures of asparaginase
Updated on 02-February-2015
Proteopedia Page Contributors and Editors (what is this?)
Joel L. Sussman, Michal Harel, Alexander Berchansky, Jaime Prilusky
