Structural highlights
Function
[MRNC_BACSU] Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. Cleaves more efficiently on assembled 50S ribosomal subunits. Cleavage is strongly stimulated by ribosomal protein L3 (RplC); 20-30% DMSO can replace RplC, suggesting RplC may alter rRNA conformation.[1]
References
- ↑ Redko Y, Bechhofer DH, Condon C. Mini-III, an unusual member of the RNase III family of enzymes, catalyses 23S ribosomal RNA maturation in B. subtilis. Mol Microbiol. 2008 Jun;68(5):1096-106. doi: 10.1111/j.1365-2958.2008.06207.x., Epub 2008 Mar 19. PMID:18363798 doi:http://dx.doi.org/10.1111/j.1365-2958.2008.06207.x
