Structural highlights
Function
[HXK1_ARATH] Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells.[1] [2] [3]
References
- ↑ Moore B, Zhou L, Rolland F, Hall Q, Cheng WH, Liu YX, Hwang I, Jones T, Sheen J. Role of the Arabidopsis glucose sensor HXK1 in nutrient, light, and hormonal signaling. Science. 2003 Apr 11;300(5617):332-6. PMID:12690200 doi:http://dx.doi.org/10.1126/science.1080585
- ↑ Kim M, Lim JH, Ahn CS, Park K, Kim GT, Kim WT, Pai HS. Mitochondria-associated hexokinases play a role in the control of programmed cell death in Nicotiana benthamiana. Plant Cell. 2006 Sep;18(9):2341-55. Epub 2006 Aug 18. PMID:16920781 doi:http://dx.doi.org/10.1105/tpc.106.041509
- ↑ Jang JC, Leon P, Zhou L, Sheen J. Hexokinase as a sugar sensor in higher plants. Plant Cell. 1997 Jan;9(1):5-19. PMID:9014361 doi:http://dx.doi.org/10.1105/tpc.9.1.5
