Defensin

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Defensins (DEF) are small cationic defense proteins active against bacteria, fungi and viruses. DEF contains 6-8 conserved cysteine residues. DEF binds to microbial cell membrane forming pores and thus allowing outflow of essential nutrients. There is increase in α-DEF in chronic inflammations and several cancers. For details on plant DEF see Plant defensin.

3D structures of defensin

Updated on 22-March-2015

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Michal Harel, Alexander Berchansky

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