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Eukaryotic initiation factor

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Eukaryotic initiation factors (EIF) are involved in the initiation of protein translation. They form a complex with the small subunit of the ribosome and Met-tRNA which scans the mRNA and recognizes the initiation codon AUG. EIF domains include the N terminal domain (NTD), C terminal domain (CTD), RNA recognition domain, middle domain, PAZ domain of EIF2C and a protein-protein interaction domain (PCI) of EIF3. For details on EIF4 see C-terminal portion of human eIF4GI.

3D structures of eukaryotic initiation factor

Updated on 01-April-2015

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