Glycosyltransferase

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Glycosyltransferase (GT) are enzymes which catalyze the transfer of monosaccharide to alcohol, carbohydrate, protein or inorganic phosphate. Galactosyltransferase (AGT) is a GT which catalyzes the transfer of galactose during the synthesis of polysaccharides. Fucosylglycoprotein 3-AGT (GTB) or histo-blood group ABO system transferase is the basis of the blood ABO system. It involves 3 carbohydrate antigens: A, B and H. Individuals with blood type A, B and AB has glycosyltransferase activitiy which converts antigen H to A or B. Individuals with blood type O lack this activity.