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Function
The protein Thioredoxin Reductase is utilized in the regulation of DNA translation and in apoptosis. A normal stop codon (UGA, UAA, and UAG) stops the translation of the mRNA, but in the presence of TrxR an extra Selenocysteine is added to the end of the protein chain. This extra amino acid is what marks the structure for death inside the cell. Enough of these structures in the cell and the entire cell will undergo apoptosis.
Disease
When left unregulated cell death does not perform as functioned resulting in a build-up of tissue and most often the cause of tumorous growths in the body. This includes cancerous growths as well as non-cancerous.
Relevance
Structural highlights
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
