Gal3-Gal80-Gal4

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Yeast Gal4 complex with DNA and Zn+2 ions 1d66

Ligands:

Structural annotation:
Resources:	CATH : 1D66B01 InterPro : Ipr007219, Ipr005600, Ipr001138, Ipr002409 Pfam : PF00172, PF03902 SCOP : d1d66a2, d1d66a1, d1d66b1, d1d66b2 UniProt : P04386

Functional annotation:
Cellular component:	nucleus
Biological process:	carbohydrate metabolic process positive regulation of transcription by galactose transcription galactose metabolic process regulation of transcription, DNA-dependent
Molecular function:	transcription factor activity DNA binding metal ion binding transcription activator activity zinc ion binding

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Gal3-Gal80-Gal4 proteins of yeast comprise a signal transducer that controls the galactose-inducible Gal4-mediated transcription activation of GAL regulon genes. In the absence of galactose Gal80 binds to Gal4 and prohibits it from activating transcription. In the presence of galactose, Gal3 binds to Gal80 to prohibit its inhibition of Gal4. For Gal4 details see User:Amir Mitchell/Gal4.

The Gal4 protein consists of a of identical subunits.