4nxr

Structural highlights

Function

[TIAM1_HUMAN] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. [NRX2B_HUMAN] Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.