Retinoblastoma-binding protein

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Retinoblastoma-binding protein (RBBP) or histone-binding protein are nuclear proteins implicated in the regulation of transcription and differentiation by the retinoblastoma tumor suppressor protein.

  • RBBP1 regulates transcriptional activity.
  • RBBP2 demethylates histone H3 at lysine 4.
  • RBBP5 is involved in methylation and dimethylation of histone H3.
  • RBBP9 blocks the binding of retinoblastoma protein to one of its signaling partners.

3D structures of retinoblastoma-binding protein

Updated on 27-May-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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