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3b7o
From Proteopedia
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| , resolution 1.60Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | PTPN11, PTP2C, SHPTP2 (Homo sapiens) | ||||||
| Activity: | Protein-tyrosine-phosphatase, with EC number 3.1.3.48 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site
Disease
Known diseases associated with this structure: Leopard syndrome OMIM:[176876], Leukemia, juvenile myelomonocytic OMIM:[176876], Noonan syndrome 1 OMIM:[176876]
About this Structure
3B7O is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:56:49 2008
Categories: Homo sapiens | Protein-tyrosine-phosphatase | Single protein | Arrowsmith, C H. | Barr, A. | Delft, F von. | Edwards, A M. | Elkins, J. | King, O. | Knapp, S. | Niesen, F. | Patel, A. | Pilka, E S. | SGC, Structural Genomics Consortium. | Salah, E. | Savitsky, P. | Ugochukwu, E. | Weigelt, J. | MLT | Alternative splicing | Cytoplasm | Deafness | Disease mutation | Hydrolase | Phosphorylation | Protein phosphatase | Ptpn11 | Sgc | Sh2 domain | Shp2 | Structural genomic | Structural genomics consortium | Tyrosine phosphatase
