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Thioredoxin

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Image:1ert.png

Crystal Structure of Thioredoxin 1ert

Template:STRUCTURE 3kd0

Thioredoxin (Trx) is an enzyme which facilitates the reduction of proteins by cysteine thiol-disulfide exchange. They contain a CXXC motif.

Trx-1 is a mammalian cellular protein.
Trx-2 is mitochondria-specific.

In higher plants, Trx are divided to 6 groups based on their sequence. Trx M, X and Y are found in prokaryotes while F, H and O are found in eukaryotes.