From Proteopedia
proteopedia linkproteopedia link | Hepatocyte growth factor activator (HGFA) is a serine protease which links tissue injury to activation of hepatocyte growth factor (HGF). HGFA converts HGF from its latent single-chain form to a heterodimeric active form. HGFA is synthesized as an inactive precursor which is converted to a heterodimer via proteolysis as a result of tissue injury.
Function
Disease
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Structural highlights
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3D Structures of hepatocyte growth factor activator
Updated on 02-July-2015
1ybw – hHGFA protease domain – human
1yc0 – hHGFA protease domain + Kunitz-type protease inhibitor
2r0k – hHGFA protease domain + antibody light chain
2r0l, 2wub, 2wuc, 3k2u – hHGFA protease domain + antibody
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