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Cytochrome P450

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Revision as of 10:00, 2 July 2015 by Michal Harel (Talk | contribs)
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Cytochrome P450 (P450) catalyzes the oxidation of organic substances like lipids. catalyzes the oxidation of organic substances like lipids. The P450 contains a heme cofactor. The protein is numbered by its gene. For details on the human P45019 family see Aromatase.

  • P450cam, also known as camphor 5-monooxygenase, catalyzes the hydroxylation of camphor.
  • P450nor is a Nitric Oxide Reductase P450.
  • P450epoK converts epothilone D to epothilone B.
  • P450cin monooxygenates 1,8-cineole which is similar to camphor.
  • Bifunctional P450/NADPH P450 reductase (P450 BM3) is a fatty acid monooxygenase.

Additional details in Drug Metabolism by CYP450 Enzymes.

3D Structures of Cytochrome P450

Updated on 02-July-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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