2amt

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Image:2amt.gif


PDB ID 2amt

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, resolution 2.30Å
Ligands: , and
Gene: ispF, mecS (Escherichia coli)
Activity: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, with EC number 4.6.1.12
Coordinates: save as pdb, mmCIF, xml



Structure of 2C-Methyl-D-Erythritol 2,4-Clycodiphosphate Synthase complexed with a CDP derived fluorescent inhibitor


About this Structure

2AMT is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy., Crane CM, Kaiser J, Ramsden NL, Lauw S, Rohdich F, Eisenreich W, Hunter WN, Bacher A, Diederich F, Angew Chem Int Ed Engl. 2006 Feb 6;45(7):1069-74. PMID:16392111

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