1x43

Structural highlights

Function

[SHLB1_MOUSE] May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Yang JS, Zhang L, Lee SY, Gad H, Luini A, Hsu VW. Key components of the fission machinery are interchangeable. Nat Cell Biol. 2006 Dec;8(12):1376-82. Epub 2006 Nov 5. PMID:17086176 doi:http://dx.doi.org/10.1038/ncb1503